The Journal of Organic Chemistry

Potential bile acid metabolites. 6. Stereoisomeric 3, 7-dihydroxy-5. beta.-cholanic acids

T Iida, FC Chang

Index: Iida, Takashi; Chang, Frederic C. Journal of Organic Chemistry, 1982 , vol. 47, # 15 p. 2966 - 2972

Full Text: HTML

Citation Number: 28

Abstract

New synthetic routes to the four possible 3, 7-dihydroxy acids are described. The principal reactions involved were inversions with DMF and MezSO-crown ether and reduction of 12- oxo tosylhydrazones. Inversion of 3a-tosylates by the Me2SO-crown ether method succeeded but that of the corresponding mesylates did not. A table of'H NMR chemical shift reference data of monosubstituted methyl cholanates pertinent to bile acid ...

Related Articles:

Novel approach to determining the absolute configurations at the C3-positions of various types of sterols based on an induced circular dichroism

[Fujiwara, Toshio; Taniguchi, Yuka; Katsumoto, Yukiteru; Tanaka, Takeyuki; Ozeki, Minoru; Iwasaki, Hiroki; Node, Manabu; Yamashita, Masayuki; Hosoi, Shinzo Steroids, 2012 , vol. 77, # 12 p. 1198 - 1204]

Bile acids LXIX. Selective K-Selectride reduction of 3, 7-diketo steroids

[Tal, Daniel M.; Frisch, G. Douglas; Elliott, William H. Tetrahedron, 1984 , vol. 40, # 5 p. 851 - 854]

Potential bile acid metabolites. 6. Stereoisomeric 3, 7-dihydroxy-5. beta.-cholanic acids

[Journal of Organic Chemistry, , vol. 47, # 15 p. 2966 - 2972]

Potential bile acid metabolites. 6. Stereoisomeric 3, 7-dihydroxy-5. beta.-cholanic acids

[Journal of Organic Chemistry, , vol. 47, # 15 p. 2966 - 2972]

Efficient lipase-catalyzed preparation of long-chain fatty acid esters of bile acids: biological activity and synthetic application of the products

[Bioscience, Biotechnology and Biochemistry, , vol. 60, # 12 p. 2059 - 2063]

More Articles...