Tetrahedron

Novel tryptophan-derived dipeptides and bioactive metabolites from the sea hare Aplysia dactylomela

DR Appleton, RC Babcock, BR Copp

Index: Appleton, David R; Babcock, Russell C; Copp, Brent R Tetrahedron, 2001 , vol. 57, # 51 p. 10181 - 10189

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Citation Number: 30

Abstract

Dactylamides A (1) and B (2), two new tryptophan-derived dipeptides were isolated from the sea hare Aplysia dactylomela and structurally characterised by spectroscopic methods and synthesis of deoxy-analogues. Isolaurenisol, allolaurinterol, their respective acetates and aplysioviolin, isolated as the bioactive constituents of the sea hare, were also structurally characterised and evaluated in a range of biological assays.

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