1H-Benzotriazol-1-yl methanesulfonate: A regioselective N-mesylating reagent

SY Kim, ND Sung, JK Choi, SS Kim

Index: Kim, Sun Young; Sung, Nack-Do; Choi, Joong-Kwon; Kim, Sung Soo Tetrahedron Letters, 1999 , vol. 40, # 1 p. 117 - 120

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Citation Number: 15

Abstract

1H-Benzotriazol-1-yl methanesulfonate has been found to be an effective reagent in selective mesylation for differentiating amino groups from one another. In a molecule with both primary and secondary amino groups, mesylation only occurred at the primary amino group. When a compound contains both amino and hydroxy groups, the reagent selectively mesylated at the amino groups.