Palladium-catalyzed double-carbonylation of alkenyl halides with secondary amines to give α-keto amides

…, H Yanagihara, F Ozawa, A Yamamoto

Index: Son, Tae-il; Yanagihara, Hisayoshi; Ozawa, Fumiyuki; Yamamoto, Akio Bulletin of the Chemical Society of Japan, 1988 , vol. 61, p. 1251 - 1258

Full Text: HTML

Citation Number: 32

Abstract

The double-carbonylation reaction of alkenyl halides with diethylamine in the presence of palladium catalysts has been examined in detail. The reaction gives α-keto amide together with amide, the single-carbonylation by-product. The yield of α-keto amide is strongly dependent on the nature of alkenyl halide. Alkenyl bromides or iodides having phenyl group (s) as substituent (s) on the vinyl group are successfully double-carbonylated under ...

Related Articles:

RhIII??Catalyzed Oxidative Olefination of Vinylic C H Bonds: Efficient and Selective Access to Di??unsaturated α??Amino Acid Derivatives and Other Linear 1, 3?? …

[Besset, Tatiana; Kuhl, Nadine; Patureau, Frederic W.; Glorius, Frank Chemistry - A European Journal, 2011 , vol. 17, # 26 p. 7167 - 7171]

Tandem conjugate addition-aldol reaction to α, β-unsaturated esters and ketones using titanium amide

[Hosomi, Akira; Yanagi, Toshiharu; Hojo, Makoto Tetrahedron Letters, 1991 , vol. 32, # 21 p. 2371 - 2374]

«Push??Pull»??Acetylene als Hilfsmittel zur Synthese von Amiden

[Neuenschwander,M. et al. Helvetica Chimica Acta, 1978 , vol. 61, p. 2428 - 2436]

More Articles...