Heterocyclic Basic Compounds. XIV. 4-Phenyl-4-(3-pyridyl)-6-dimethylamino-3-hexanone1

HS Mosher, JE Tessieri

Index: Mosher; Tessieri Journal of the American Chemical Society, 1951 , vol. 73, p. 4925

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Citation Number: 26

Abstract

Panizzon3s4 has condensed 2-and 4-halopyridines with phenylEPcetonitrile in the presence of sodium amide but did not extend the reaction to the 3-isomer, presumably because of the well-recognized aromatic nature of the 3-position in the pyridine rmg. It has been found, however, that 3-bromopyridine is readily converted into a-phenyl-a-(3-pyridyl)- acetonitrile by this reaction. This was converted to 4-phenyl-4-(3-pyridy1)-6- ...