Chiroptical properties of cyclic amines

G Bettoni, F Morlacchi, R Perrone…

Index: Bettoni; Morlacchi; Perrone; et al. Journal of Heterocyclic Chemistry, 1979 , vol. 16, # 3 p. 591 - 594

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Citation Number: 4

Abstract

Abstract Chiroptical properties of several 2 or 3 monosubstituted azetidines, pyrrolidines and piperidines as free bases and N-[2-pyridyl N-oxide] derivatives has been examined. The absolute configuration can be unambiguously established, independently on the nature of the substituent and the size of the ring, only for 2-substituted N-[2-pyridyl N-oxide] amine derivatives. This behaviour is explained in terms of limited rotational freedom in these ...