Natural products in parallel synthesis: triazole libraries of nonactic acid

…, A Nayek, AE Smith, BR Kusche, SC Bergmeier…

Index: Luesse, Sarah B.; Wells, Gregg; Nayek, Abhijit; Smith, Adrienne E.; Kusche, Brian R.; Bergmeier, Stephen C.; McMills, Mark C.; Priestley, Nigel D.; Wright, Dennis L. Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 14 p. 3946 - 3949

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Citation Number: 19

Abstract

The development of pharmaceutical agents often relies on compounds prepared from natural products or structures inspired by natural products. 1 and 2 We have been interested in straightforward synthetic methods that combine the stereochemical and topological complexity of natural product scaffolds with the diverse analogue generation available from combinatorial synthesis to produce diverse, pharmacologically interesting compounds. ... Methanolysis of nonactin followed ...