Reimer–Tiemann Reaction of Coumarins

SC Bhunia, GC Patra, SC Pal

Index: Bhunia, Sankar C.; Patra, Gopal C.; Pal, Sudhir C. Synthetic Communications, 2011 , vol. 41, # 24 p. 3678 - 3682

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Citation Number: 5

Abstract

Abstract Improved yields of aldehydes from the Reimer–Tiemann reaction of coumarin and two of its derivatives, namely 7-methylcoumarin and 3, 4-benzocoumarin, are obtained by carrying the reaction in a two-step procedure. Using crown ether as phase transfer catalyst, a further improvement in the yield of products is achieved. Additionally, coumarin and 7- methylcoumarin are shown to give dialdehydes under this condition. Dialdehydes are ...