Synthesis and study of the antibacterial and antifungal activity of 1, 2-substituted hydrazines

AM Demchenko, VA Chumakov, AN Krasovskii…

Index: Demchenko; Chumakov; Krasovskii; Musich; Lozinskii Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 6 p. 311 - 313

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Abstract

Within the framework of the search for new antibacterial and antifungal agents, we have studied interactions of the methyl esters of 2-(2-benzimidazolylthio)acetic and 2-(2- benzimidazolylthio)propionic acids (Ia, Ib) [1, 2], and of the hydrazides of 2-benzimidazolyl- and 1-methyl-(2-benzimida- zolylthio)acetic acids (Ia, IIb) [1, 2], with cyclohexylisothio- cyanate, phenylisothiocyanate, 2-ethoxy-3,4,5,6-tetrahy- dropyridine, and 2-methoxy-4,5,6,7- ...