Synthesis

Synthesis of sterically hindered polychlorinated biphenyl derivatives

…, SM Vyas, MW Duffel, S Parkin, HJ Lehmler

Index: Joshi; Vyas; Duffel; Parkin; Lehmler Synthesis, 2011 , # 7 p. 1045 - 1054

Full Text: HTML

Citation Number: 13

Abstract

Abstract A series of sterically hindered (methoxylated) polychlorinated biphenyl derivatives were synthesized using the Suzuki and the Ullmann coupling reactions. The Suzuki coupling with Pd (dba) 2/2-dicyclohexylphosphino-2′, 6′-dimethoxybiphenyl (DPDB) gave better yields (65-98%) compared to the classic Ullmann coupling reaction (20-38%). Despite the reactive catalyst system, no significant coupling with aromatic chlorine ...