Peptide backbone-to-backbone cyclisation as an avenue to β-turn mimics

…, CW Joukema, GN Wagenaars, HCJ Ottenheijm

Index: Hermkens; Dinther; Joukema; Wagenaars; Ottenheijn Tetrahedron Letters, 1994 , vol. 35, # 49 p. 9271 - 9274

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Citation Number: 13

Abstract

Abstract 1, 3-Dipolar cycloaddition of the nitrone functionality of 13 and the alkene functionality of 8 yields the backbone-to-backbone cyclised peptides 14–16. The conformation of these structures is such that they are β-turn mimics. They differ in their Full- size image (< 1 K)