Practical and General Entry to N??Tosyl Aryl Aldimines Promoted by Sulfamic Acid in Water and Alcohol

Z Li, X Ren, Y Shi, P Ouyang

Index: Li, Zhenjiang; Ren, Xinhua; Shi, Yuhu; Ouyang, Pingkai Synthetic Communications, 2007 , vol. 37, # 5 p. 713 - 724

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Citation Number: 7

Abstract

Abstract A practical, indirect procedure composed of a three??component condensation using aromatic aldehydes, p??tosylamide, and sodium p??toluenesulfinate in the presence of sulfamic acid in tap water–alcohol solvents to afford amidosulfones, and the subsequent water two??phase basic elimination of the amidosulfones to N??tosyl arylimines, was developed. The process has little environmental impact, easy workup, mild reaction ...