Canadian Journal of Chemistry

A short formal total synthesis of (±)-hirsutic acid

G Revol, C Fuchs, SZ Zard

Index: Revol, Guillaume; Fuchs, Christian; Zard, Samir Z. Canadian Journal of Chemistry, 2012 , vol. 90, # 11 p. 927 - 931

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Abstract

A short formal total synthesis of (±)-hirsutic acid is described using a Claisen rearrangement and a radical cascade as the key steps. The radical sequence involves an intermolecular addition of a radical derived from a xanthate followed by a cyclization and transfer of the xanthate group.

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