Angewandte Chemie International Edition

Copper??Catalyzed Rearrangement of Tertiary Amines through Oxidation of Aliphatic C H Bonds in Air or Oxygen: Direct Synthesis of α??Amino Acetals

JS Tian, TP Loh

Index: Tian, Jie-Sheng; Loh, Teck-Peng Angewandte Chemie - International Edition, 2010 , vol. 49, # 45 p. 8417 - 8420

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Citation Number: 57

Abstract

Many natural products or biomolecules contain α-amino acid or β-amino alcohol units in their structures.[1] Although these units may be obtained from naturally occurring α-amino acids, general methods for the synthesis of other non-natural α-amino acids are highly sought after. Among many reported approaches, the direct synthesis of α-amino acids in air by means of biomimetic methods has been regarded as one of the most challenging tasks. ...

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