Synthesis of some tolperisone metabolites in racemic and optically active form

…, Á Demeter, K Temesvári-Takács, E Fogassy

Index: Balint, Jozsef; Egri, Gabriella; Markovits, Imre; Czugler, Matyas; Marthi, Katalin; Demeter, Adam; Temesvari-Takacs, Krisztina; Fogassy, Elemer Tetrahedron Asymmetry, 2002 , vol. 12, # 24 p. 3417 - 3422

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Citation Number: 5

Abstract

1-(4′-Carboxyphenyl)-2-methyl-3-(piperidine-1-yl)-propan-1-one M3, erythro-1-(4′- carboxyphenyl)-2-methyl-3-(piperidine-1-yl)-propan-1-ol M4 and threo-1-(4′- carboxyphenyl)-2-methyl-3-(piperidine-1-yl)-propan-1-ol M5, metabolites of the muscle relaxant tolperisone were synthesized in racemic and optically active forms.