Synthesis of optically active chloro alkanoic esters

U Azzena, G Delogu, G Melloni, O Piccolo

Index: Azzena, Ugo; Delogu, Giovanna; Melloni, Giovanni; Piccolo, Oreste Tetrahedron Letters, 1989 , vol. 30, # 34 p. 4555 - 4558

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Citation Number: 13

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The stereospecific synthesis (optical yield up to 94%) of optically active (R)-alkyl-2-chloropropionate and (S)-alkyl-3-chlorobutanoate by the action of AlCl 3 on the corresponding (S)-2-mesyloxy - and (R)-3-mesyloxy-derivatives is described. ... Loss of optical activity up to 60% has ...