Divergent synthesis of multifunctional molecular probes to elucidate the enzyme specificity of dipeptidic γ-secretase inhibitors

H Fuwa, Y Takahashi, Y Konno, N Watanabe…

Index: Hashimoto, Makoto; Kanaoka, Yuichi; Hatanaka, Yasumaru Heterocycles, 1997 , vol. 46, # 1 p. 119 - 122

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Citation Number: 77

Abstract

... Volume: Page ... affinity ligand moiety would be particularly attractive as a solution-phase counterpart (Figure 2). Indeed, Hatanaka and co ... chloroformate followed by coupling of the derived 5 with the appropriate biotinylated amines (Scheme 1). The phenyldiazirine ...