Total Synthesis of Nortopsentins AD, Marine Alkaloids.

I Kawasaki, M YAMASHITA, S OHTA

Index: Kawasaki, Ikuo; Yamashita, Masayuki; Ohta, Shunsaku Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 10 p. 1831 - 1839

Full Text: HTML

Citation Number: 132

Abstract

October 1996 temperature. The yield of 6a was measured by GLC analysis, and water (5 ml) was added to the mixture. The crude 7 was extracted with AcOEt, and the organic layer was dried and evaporated to give a solid residue, which was subjected to PTLC (AcOEt/n-hexane: 1/5) to give 7 (44mg, 27%). This product was recrystallized from AeOEt—n-hexane. mp 222—240 "C (dec.) (colorless crystals). IR (CHC13): 2920, 1481, 1376, 1109, 967 cm' 1. 'H—NMR ( ...