Baker's yeast-mediated enantioselective synthesis of the bisabolane sesquiterpenes (+)-curcuphenol,(+)-xanthorrhizol,(−)-curcuquinone and (+)-curcuhydroquinone

C Fuganti, S Serra

Index: Fuganti, Claudio; Serra, Stefano Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 22 p. 3758 - 3764

Full Text: HTML

Citation Number: 72

Abstract

Fermenting baker's yeast converts the unsaturated aldehydes 5a–c into the saturated alcohols 6a–c, respectively. The microbial saturation of substrates adsorbed on a nonpolar resin proceeds in high chemical yields and shows complete enantioselectivity in the formation of the (S [])-(+) isomers. Enantiopure 6a–