Tetrahedron Letters

Asymmetric synthesis of (+)-passifloricin A and its 6-epimer

S Chandrasekhar, C Rambabu, AS Reddy

Index: Chandrasekhar; Rambabu; Reddy, A. Syamprasad Tetrahedron Letters, 2008 , vol. 49, # 29-30 p. 4476 - 4478

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Citation Number: 14

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Stereoselective total syntheses of the antiprotozoal natural product (+)-passifloricin A and its C-6 epimer have been achieved in ∼5% overall yield. The strategy is based on Jacobsen epoxidation, Grubbs' metathesis and an Evans' intramolecular oxa-Michael reaction.

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