Catalysis of the β-elimination of HF from isomeric 2-fluoroethylpyridines and 1-methyl-2-fluoroethylpyridinium salts. Proton-activating factors and methyl-activating …
…, V Laureti, L Ottavi, R Ruzziconi
Index: Alunni, Sergio; Laureti, Valeria; Ottavi, Laura; Ruzziconi, Renzo Journal of Organic Chemistry, 2003 , vol. 68, # 3 p. 718 - 725
Full Text: HTML
Citation Number: 25
Abstract
Second-order rate constants, k OHN, M-1 s-1, for the β-elimination reactions of HF with 2-(2- fluoroethyl) pyridine (2), 3-(2-fluoroethyl) pyridine (3), and 4-(2-fluoroethyl) pyridine (4) in OH- /H2O, at 50° C and μ= 1 M KCl, are= 0.646× 10-4 M-1 s-1,= 2.97× 10-6 M-1 s-1, and= 5.28× 10-4 M-1 s-1, respectively. When compared with the second-order rate constants for the same processes with the nitrogen-methylated substrates 1-methyl-2-(2-fluoroethyl) ...
Related Articles:
[Katritzky, Alan R.; Khan, Ghulam R.; Marson, Charles M. Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 641 - 644]
[Katritzky, Alan R.; Khan, Ghulam R.; Marson, Charles M. Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 641 - 644]
[Katritzky, Alan R.; Khan, Ghulam R.; Marson, Charles M. Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 641 - 644]
[Katritzky, Alan R.; Khan, Ghulam R.; Marson, Charles M. Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 641 - 644]
[Katritzky, Alan R.; Khan, Ghulam R.; Schwarz, Otto A. Tetrahedron Letters, 1984 , vol. 25, # 12 p. 1223 - 1226]