DERIVATIVES OF 3: 4??XYLIDINE AND RELATED COMPOUNDS AS INHIBITORS OF INFLUENZA VIRUS: RELATIONSHIPS BETWEEN CHEMICAL STRUCTURE …

RJ Clark, A Isaacs, J Walker

Index: Clark et al. Brit.J.Pharmacol., 1958 , vol. 13, p. 424

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Citation Number: 7

Abstract

METHODS Chemical Methods General Methods for the Preparation of Halogenoacylarylamides Two methods were used:(i) the appropriate amine and chloroacetyl (or a-chloropropionyl) chloride were heated together in boiling benzene for 2 hr., or (ii) the amine and chloroacetyl chloride were allowed to react in glacial acetic acid in the cold in presence of sodium acetate as described by Lofgren (1948). The following ...