Amino acids

A new non-natural arginine-like amino acid derivative with a sulfamoyl group in the side-chain

…, ML Di Gioia, A Leggio, A Liguori, F Perri, C Siciliano…

Index: De Marco, Rosaria; Di Gioia, Maria L.; Leggio, Antonella; Liguori, Angelo; Perri, Francesca; Siciliano, Carlo; Viscomi, Maria C. Amino Acids, 2010 , vol. 38, # 3 p. 691 - 700

Full Text: HTML

Citation Number: 7

Abstract

Abstract Sulfamoylation of the l-ornithine methyl ester side-chain generates a non-natural arginine isostere which can be coupled with N-Fmoc-l-proline to synthesize analogues which maintain the structural characteristics of the biologically important Pro-Arg dipeptide ...