A Highly Tunable Family of Chiral Bisphospholanes for Rh??Catalyzed Enantioselective Hydrogenation Reactions

…, H Jiao, W Baumann, A Spannenberg…

Index: Holz, Jens; Zayas, Odalys; Jiao, Haijun; Baumann, Wolfgang; Spannenberg, Anke; Monsees, Axel; Riermeier, Thomas H.; Almena, Juan; Kadyrov, Renat; Boerner, Armin Chemistry - A European Journal, 2006 , vol. 12, # 19 p. 5001 - 5013

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Citation Number: 68

Abstract

Abstract A set of 16 new and closely related bisphospholane ligands have been prepared by using a highly flexible and convergent approach. Each synthesis can be performed on an industrially relevant scale. The bisphosphines differ in the nature of the bridge connecting both phospholane units. Bridges are formed by three-, four-, five-and six-membered heterocyclic or alicyclic rings. Bisphospholanes and their Rh-precatalysts have been ...