Synthesis

Synthetic Studies on l-Proline and (4R)-Hydroxy-l-proline Derivatives

T Gonzalez, O Abad, MC Santano, C Minguillon

Index: Gonzalez, Teresa; Abad, Olga; Santano, M. Carmen; Minguillon, Cristina Synthesis, 2004 , # 8 p. 1171 - 1182

Full Text: HTML

Citation Number: 0

Abstract

Abstract The preparation of a number of l-proline and (4R)-hydroxy-l-proline derivatives to assess their enantioselectivity when applied to several techniques and experimental conditions is described. All the derivatives prepared incorporated at least one 3, 5- disubstituted aromatic ring that contained nitro, chloro or methyl groups and were obtained by classical methods. In spite of the difficulties that arise from the presence of rotational ...