Synthesis, antibacterial and antifungal activities of several new benzo-naphtho-and quinolino-1, 4-thiazine and 1, 5-thiazepine derivatives

V Ambrogi, G Grandolini, L Perioli, M Ricci…

Index: Ambrogi, V.; Grandolini, G.; Perioli, L.; Ricci, M.; Rossi, C.; Tuttobello, L. European Journal of Medicinal Chemistry, 1990 , vol. 25, # 5 p. 403 - 411

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Citation Number: 19

Abstract

Abstract The synthèsis of a number of thiosemicarbazone, phenylthiosemicarbazone, oxime and oxime O-ester derivatives of benzo-naphtho-and quinolino-1, 4-thiazines and 1, 5- thiazepines is described. All the compounds were tested in vitro for their antimicrobial activity. Compounds 4b, 5b, 5d, 5g and 8f showed interesting antifungal activity.