Microwave-assisted synthesis of nitroketene N, S-arylaminoacetals

DP Sangi, AG Corrêa

Index: Sangi, Diego P.; Correa, Arlene G. Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 5 p. 795 - 799

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Citation Number: 8

Abstract

In a ongoing program towards the synthesis of quinoxalines, we investigated the reaction of nitroethene 1 with aniline using ethanol as solvent and microwave (MW) irradiation (Scheme 1). In our first trial, we obtained 43% yield of the desired product after 30 min at 110 o C and 70 W. We then performed a series of experiments in order to optimize this result, which are summarized in Table 1. We observed that the rate of conversion of reagents increased with temperature and ...