Aldol Condensation versus Conjugate Addition. Intramolecular Cyclization Using a Combination of Lewis Acid and 1, 2-Diol.

S Yamada, H Suemune

Index: Yamada; Suemune Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 8 p. 1171 - 1175

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Citation Number: 7

Abstract

The reactivity of 3-substituted 4-methyl-4-(3-oxobutyl)-2-cyclohexen-1-ones (1) in the presence of a combination of a Lewis acid and a 1, 2-diol was studied. The results suggest several factors that influence 6-membered ring formation, including two types of