Reductive cyclization of mercurial enones

S Danishefsky, S Chackalamannil…

Index: Danishefsky, Samuel; Chackalamannil, Samuel; Uang, Biing-Jiun Journal of Organic Chemistry, 1982 , vol. 47, # 11 p. 2231 - 2232

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Citation Number: 45

Abstract

We were, therefore, struck by some findings of Giese""(eq 3) to the effect that several 8- methoxy mercurials undergo" reductive" coupling with electrophilic olefins upon treatment with sodium trimethoxyborohydride. Though proceeding presumably through a free-radical pathway, 12-14 the Giese reaction corresponds, in its overall synthetic consequence, to eq 1. We have begun to study the synthetic potentialities15J6 implicit in the reductive ...

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