Pyridazinones as selective cyclooxygenase-2 inhibitors
CS Li, C Brideau, CC Chan, C Savoie…
Index: Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 4 p. 597 - 600
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Citation Number: 62
Abstract
... Bioorganic & Medicinal Chemistry Letters. ... of 4 with 4-methylthiophenylboronic acid, followed by bromination and oxidiation yielded the 3-bromo-furan-2-one intermediate 5. This intermediate was then converted to the pyridazinone intermediate 8 using chemistry as described ...
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