Tetrahedron: Asymmetry

Highly enantioselective copper-catalyzed 1, 4-conjugate addition of diethylzinc to cyclic enones and α, β-unsaturated lactones

L Liang, M Yan, YM Li, ASC Chan

Index: Liang, Liang; Yan, Ming; Li, Yue-Ming; Chan, Albert S.C. Tetrahedron Asymmetry, 2004 , vol. 15, # 16 p. 2575 - 2578

Full Text: HTML

Citation Number: 34

Abstract

A significant improvement in enantioselectivity has been achieved in the 1, 4-additions of diethylzinc to 2-cyclopentenone, 2-cyclohexenone and 5, 6-hydro-2H-pyran-2-one (up to 93%, 98% and 94% ee, respectively) by using a chiral diphosphite–copper catalyst under suitable reaction conditions.

Ferrocene phosphane–carbene ligands in Cu-catalyzed enantioselective 1, 4-additions of Grignard reagents to α, β-unsaturated carbonyl compounds

[Csizmadiova, Jana; Meciarova, Maria; Almassy, Ambroz; Horvath, Branislav; Sebesta, Radovan Journal of Organometallic Chemistry, 2013 , vol. 737, p. 47 - 52]

Synthesis and absolute configuration of the insecticidal sesquilignan (+)-HAEDOXAN a in honour of professor GH Neil Towers 75th birthday

[Ishibashi, Fumito; Taniguchi, Eiji Phytochemistry, 1998 , vol. 49, # 2 p. 613 - 622]

Intramolecular regioselective insertion into unactivated prochiral carbon-hydrogen bonds with diazoacetates of primary alcohols catalyzed by chiral dirhodium (II) …

[Bode; Doyle; Protopopova; Zhou Journal of Organic Chemistry, 1996 , vol. 61, # 26 p. 9146 - 9155]

Highly enantioselective copper-catalyzed 1, 4-conjugate addition of diethylzinc to cyclic enones and α, β-unsaturated lactones

Abstract

Related Articles:

More Articles...