Liposome-mediated enzymatic synthesis of phosphatidylcholine as an approach to self-replicating liposomes

PK Schmidli, P Schurtenberger…

Index: Schmidli, Peter Kurt; Schurtenberger, Peter; Luisi, Pier Luigi Journal of the American Chemical Society, 1991 ,  vol. 113,  # 21  p. 8127 - 8130

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Citation Number: 76

Abstract

Abstract: The four enzymes of the salvage pathway for phosphatidylcholine synthesis sn- glycerol-3-phosphate acyltransferase, 1-acyl-sn-glycerol-3-phosphate acyltransferase, phosphatidate phosphatase, and cytidinediphosphocholine phosphocholinetransferase were simultaneously bound to soybean phosphatidylcholine liposomes. Evidence is presented that the entire enzyme chain is reconstituted in the liposomes, and that ...