A New Synthetic Route to Unsymmetrical 9??Arylxanthenes

SK Das, R Singh, G Panda

Index: Das, Sajal Kumar; Singh, Ritesh; Panda, Gautam European Journal of Organic Chemistry, 2009 , # 28 p. 4757 - 4761

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Citation Number: 11

Abstract

Abstract A facile and general three-step synthetic route towards unsymmetrical 9- arylxanthenes was developed. The reaction sequence involves nucleophilic substitution of commercially available 2-fluorobenzaldehydes with arenoxides, Grignard reaction of the resulting 2-arenoxybenzaldehydes with arylmagnesium bromides, followed by FeCl 3- catalyzed intramolecular diarylmethylation of the resulting carbinols. This strategy was ...