Journal of heterocyclic chemistry

Oxidative halogenation of substituted pyrroles with Cu (II). Part III. Bromination and chlorination of 2??benzoylpyrrole

S Petruso, S Caronna

Index: Petruso, S.; Caronna, S. Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 2 p. 355 - 357

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Citation Number: 16

Abstract

Abstract The bromination of 2-benzoylpyrrole with copper (II) bromide in the homogeneous and the heterogeneous phase is described, giving 4-and 5-monobromo derivatives whose ratio decreases as the temperature is increased. The same reaction with copper (II) chloride in acetonitrile at 60 produces 5-chloro-2-benzoylpyrrole as the major product. 4, 5- Dihalopyrroles in good yields are obtained with an excess of halogenating agent.