Enantioselective epoxidation of cyclic 1, 3-dienes catalyzed by a sterically and electronically optimized (salen) Mn complex

S Chang, RM Heid, EN Jacobsen

Index: Chang, Sukbok; Heid, Richard M.; Jacobsen, Eric N. Tetrahedron Letters, 1994 , vol. 35, # 5 p. 669 - 672

Full Text: HTML

Citation Number: 122

Abstract

Abstract Chiral (salen) Mn (III) Cl complexes catalyze epoxidation of cyclic 1, 3-dienes with moderate-to-good enantioselectivity. A new catalyst (2), bearing sterically hindered and electron donating OSi (iPr) 3 (OTIPS) substituents, induces up to 12% higher selectivity than the previously-reported tert-butyl substituted analog 1.