Tetrahedron letters

A new method to extend dimercaptan or diamine chains with aminopropyl units using 3-bromo-N-tritylpropanamine

KE Krakowiak, P Huszthy, JS Bradshaw, RM Izatt

Index: Krakowiak, Krzysztof E.; Huszthy, Peter; Bradshaw, Jerald S.; Izatt, Reed M. Tetrahedron Letters, 1991 , vol. 32, # 1 p. 21 - 22

Full Text: HTML

Citation Number: 4

Abstract

Abstract Dimercaptans and diamines react with 3-bromo-N-tritylpropanamine to give the corresponding N, N′-ditrityldithia and N, N′-ditritylpolyaza compounds in yields of 50– 80%. The trityl protecting groups are readily removed in acid. These reactions make possible the synthesis of a number of new α-ω-diamino compounds needed for the synthesis of new dithiadiaza, di-and polyaza macrocyclic ligands.