7, 12-Dihydropleiadenes. II. Conformational Analysis of Some 7-Substituted 7, 12-Dihydropleiadenes1

PT Lansbury, JF Bieron, AJ Lacher

Index: Lansbury,P.T. et al. Journal of the American Chemical Society, 1966 , vol. 88, p. 1482 - 1488

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Citation Number: 15

Abstract

Abstract: The syntheses of 7-chloro-, 7-methoxy-, and?-acetoxy-7, 12-dihydropleiadenes have been accomplished and the conformational preferences of these groups, as well as a 7- phenyl group, established as axial. Evidence for these conclusions is obtained from nmr spectroscopy, using conformationally homogeneous model 7, 12-dihydropleiadenes of known stereochemistry, and evaluation of long-range coupling between C, and Clz ...