Synthesis, surface tension properties and antibacterial activities of amphiphilic D-galactopyranose derivatives

L Chaveriat, I Gosselin, C Machut, P Martin

Index: Chaveriat, Ludovic; Gosselin, Isabelle; Machut, Cecile; Martin, Patrick European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 177 - 186

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Citation Number: 9

Abstract

Several amphiphilic d-galactopyranose derivatives were synthesized in which the glycosidic moiety was separated from the hydrophobic alkyl chain (along 8 or 12 carbon atoms) by a spacer arm (butyl, butynyl or benzyl) in order to increase their surfactant properties and to obtain new antibacterial compounds. The surface tensions of the products were analyzed by Critical Micelle Concentration (CMC) and γCMC measurements and the antimicrobial ...