Synthesis

Microwave-assisted C-5 iodination of substituted pyrimidinones and pyrimidine nucleosides

L Paolini, E Petricci, F Corelli, M Botta

Index: Paolini, Lisa; Petricci, Elena; Corelli, Federico; Botta, Maurizio Synthesis, 2003 , # 7 p. 1039 - 1042

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Citation Number: 27

Abstract

Abstract Direct microwave-assisted iodination of several pyrimidinones and pyrimidine nucleosides with N-iodosuccinimide to give the corresponding 5-iodo derivatives is described. Application of this reaction to polymer-bound pyrimidinones was also investigated.