Journal of Chemical Sciences

Proximity effect on the general base catalysed hydrolysis of amide linkage: The role of cationic surfactant, CTABr

SC Dash, AC Dash

Index: Dash, Sarat C.; Dash, Anadi C. Journal of Chemical Sciences, 2011 , vol. 123, # 4 p. 497 - 507

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Abstract

Abstract. The bis phenoxide forms of (1, 2) bis (2-hydroxybenzamido) ethane (I),(1, 5) bis (2- hydroxybenzamido) 3-azapentane (II),(1, 3) bis (2-hydroxybenzamido) propane (III), and (1, 8) bis (2-hydroxybenzamido) 3, 6-diazaoctane (IV) undergo facile hydrolysis of one of the amide groups (0.02≤[OH−] T (mol dm− 3)≤ 0.5, 10% MeOH (v/v)+ H 2 O medium) without exhibiting [OH−] dependence. The reactivity trend follows I~ II>> III~ IV with low activation ...