Antibacterial and antifungal activities of new pyrazolo [3, 4-d] pyridazin derivatives

E Akbas, I Berber

Index: Akbas, Esvet; Berber, Ismet European Journal of Medicinal Chemistry, 2005 , vol. 40, # 4 p. 401 - 405

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Citation Number: 121

Abstract

Several new pyrazolo [3, 4-d] pyridazin derivatives were prepared by the reaction of two new 1H-pyrazole-3-carboxylic acids and various hydrazines. The compounds were tested for antimicrobial activities against Gram-negative, Gram-positive bacteria and fungi. The compounds named as 7e, f had the highest antimicrobial activities against Gram-negative, Gram-positive bacteria and fungi with minimum inhibitory concentrations in the range of ...