The Journal of organic chemistry

An efficient synthesis of enantiomerically pure (R)-pipecolic acid,(S)-proline, and their N-alkylated derivatives

A Fadel, N Lahrache

Index: Bajgrowicz, Jerzy; Achquar, Abdelrhani El; Roumestant, Marie-Louise; Pigiere, Christian; Viallefont, Philippe Heterocycles, 1986 , vol. 24, # 8 p. 2165 - 2167

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Citation Number: 26

Abstract

... Volume: Page: ... The same reaction sequence, applied to amide (R,R)-8, afforded the pipecolinamide (R)-20 ([α] D +33.1 (c 2.00, EtOH)) and ... This approach can be used in the synthesis of other heterocyclic rings, a possibility that is currently being explored in our ...

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