Tetrahedron

Efficient synthesis of 4-phosphinoyl-4, 5, 6, 7-tetrahydro-2H-indazol-3-ylamines

N Jelaiel, C Comoy, B Fernette, ML Efrit, Y Fort

Index: Jelaiel, Nourchaine; Comoy, Corinne; Fernette, Brigitte; Efrit, Mohamed Lofti; Fort, Yves Tetrahedron, 2011 , vol. 67, # 48 p. 9440 - 9445

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Citation Number: 26

Abstract

Because of their chemical and/or biological significance, nitrogen containing heterocycles represent an important and attractive area of organic chemistry. Among various series of heterocycles, we focused our attention on indazolyl moieties. As mentioned in literature, numerous examples of indazolyl heterocycles exhibit biological properties as well as anticoagulating agent, 1 topoisomerase bacterium II inhibitor, 2 or for treatment of hypercholesterol, 3 tuberculosis, 4 … (Fig. 1).

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