Journal of heterocyclic chemistry

Cyclization of 2??and 3??indolylthiobenzoic, phenylacetic and nicotinic acids and esters to novel indole??containing tetracyclic ring systems

P Hamel, M Girard, NN Tsou

Index: Hamel, Pierre; Girard, Mario; Tsou, Nancy N. Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 3 p. 643 - 652

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Citation Number: 12

Abstract

Abstract A series of 2-and 3-indolylthio benzoic, phenylacetic and nicotinic acids or esters were cyclized under dehydrative conditions affording several tetracyclic indole-containing ketones, several of which constitute the first reported examples of novel ring systems, such as the [1] benzothiepino [2, 3-b] and [3, 2-b] indole and the pyrido [3′ 2′: 5, 6] and [3′ 4′: 5, 6] thiopyrano [2, 3-b] and [3, 2-b] indole as well as the [3′ 2′: 5, 6] and [3′ 4′: 5 ...