Concave reagents, 3. Synthesis, basicity, and conformation of new concave pyridines

U Lüning, R Baumstark, K Peters…

Index: Luening, Ulrich; Baumstark, Roland; Peters, Karl; Schnering, Hans Georg von Liebigs Annalen der Chemie, 1990 , # 2 p. 129 - 143

Full Text: HTML

Citation Number: 19

Abstract

Abstract Eight new bimacrocyclic concave pyridines 9 and six monomacrocyclic and open- chain analogues 10–12 were synthesized in overall yields up to 40%(up to 75% for nonmacrocyclic pyridines) starting from 2, 6-pyridinedicarbaldehydes 1, diamines 2 and diacyl dichlorides 7. Their basicities cover a range of more than three orders of magnitude. They are determined not only by the substitution pattern of the pyridine ring, but also by ...