Tetrahedron

The synthesis of N-arylcyclopropylamines via palladium-catalyzed C–N bond formation

W Cui, RN Loeppky

Index: Cui, Wenge; Loeppky, Richard N Tetrahedron, 2001 , vol. 57, # 15 p. 2953 - 2956

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Citation Number: 26

Abstract

A variety of N-arylcyclopropylamines has been prepared in one step, by the Pd2 (dba) 3/BINAP/NaOtBu-catalyzed amination of an aryl bromide with cyclopropylamine. Compounds bearing the N-aryl substitutent (phenyl, 4-methylphenyl, 2-methoxyphenyl, 3-