Enhanced chromatographic resolution of alcohol enantiomers as phosphate or phosphonate derivatives

Y Leblanc, C Dufresne, R Carson, L Morency…

Index: Leblanc, Yves; Dufresne, Claude; Carson, Rebekah; Morency, Louis; Welch, Christopher J Tetrahedron Asymmetry, 2001 , vol. 12, # 22 p. 3063 - 3066

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Citation Number: 10

Abstract

HPLC using a chiral support is a powerful analytical method for measuring enantioenrichment. 1., , , and In cases where sufficient resolution is obtained, chiral HPLC may also be used for the isolation of useful quantities of enantiopure materials. 2., and For poorly resolved mixtures of enantiomers, conversion to more readily resolved derivatives is often possible. 3., , and While this approach has lost some favor in recent years as the ability to ...