N-3-substituted pyrimidinones as potent, orally active, AT1 selective angiotensin II receptor antagonists

A Salimbeni, R Canevotti, F Paleari…

Index: Journal of Medicinal Chemistry, , vol. 38, # 24 p. 4806 - 4820

Full Text: HTML

Citation Number: 53

Abstract

... Considerable efforts in the design and synthesis of novel analogues of this lead compound have been performed by several pharmaceutical laboratories. ... f No BSA was included in the assay mixture. Page 5. 4810 Journal of Medicinal Chemistry, 1995, Vol. 38, No. 24 ...

Related Articles:

A metathesis approach to aromatic heterocycles

[European Journal of Organic Chemistry, , # 10 p. 1969 - 1971]

Studies dealing with the excited-state behavior of substituted 8-oxabicyclo [3.2. 1] oct-6-en-2-ones

[Journal of Organic Chemistry, , vol. 56, # 3 p. 1077 - 1083]

Synthesis of 3-acyl and 3-carboalkoxyfurans by the ceric ammonium nitrate promoted addition of 1, 3-dicarbonyl compounds to vinylic acetates

[Synthetic Communications, , vol. 18, # 15 p. 1841 - 1846]

Synthesis of 3-acyl and 3-carboalkoxyfurans by the ceric ammonium nitrate promoted addition of 1, 3-dicarbonyl compounds to vinylic acetates

[Synthetic Communications, , vol. 18, # 15 p. 1841 - 1846]

More Articles...