Tetrahedron Letters

A green one-pot multicomponent synthesis of 4H-pyrans and polysubstituted aniline derivatives of biological, pharmacological, and optical applications using silica …

S Banerjee, A Horn, H Khatri, G Sereda

Index: Banerjee, Subhash; Horn, Alissa; Khatri, Hari; Sereda, Grigoriy Tetrahedron Letters, 2011 , vol. 52, # 16 p. 1878 - 1881

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Citation Number: 119

Abstract

A one-pot practical, efficient, and environmentally benign multicomponent synthesis of 4H- pyrans and polysubstituted aniline derivatives of biological, pharmacological, and optical applications has been developed using a very mild, neutral, and reusable silica nanoparticles as catalyst. The 4H-pyran derivatives were synthesized by a three component reaction of an aldehyde, malononitrile, and 5, 5-dimethyl-1, 3-cyclohexanedione or ethyl ...