Phytochemistry

Effect of nifedipine on alkaloid accumulation in Catharanthus roseus cell cultures

JM Merillon, D Liu, Y Laurent, M Rideau, C Viel

Index: Merillon, J. M.; Liu, D.; Laurent, Y.; Rideau, M.; Viel, C. Phytochemistry (Elsevier), 1992 , vol. 31, # 5 p. 1609 - 1612

Full Text: HTML

Citation Number: 12

Abstract

Abstract The effect of nifedipine on both alkaloid accumulation and calcium uptake in Catharanthus roseus cell cultures was investigated. It was shown that nifedipine inhibited ajmalicine accumulation through a mechanism other than blocking of the calcium channel uptake. Moreover, nifedipine was biotransformed into its 4-(2′-aminophenyl)-pyridine derivative.

Related Articles:

The protection of Nifedipin from photodegradation due to complex formation with β-cyclodextrin

[Nikolic, Vesna; Ilic, Dusica; Nikolic, Ljubisa; Stankovic, Mihajlo; Cakic, Milorad; Stanojevic, Ljiljana; Kapor, Anges; Popsavin, Mirjana Central European Journal of Chemistry, 2010 , vol. 8, # 4 p. 744 - 749]

Photochemistry of 4??(2??Nitrophenyl)??1, 4??Dihydropyridines. Evidence for Electron Transfer and Formation of an Intermediate

[Fasani, Elisa; Dondi, Daniele; Ricci, Andrea; Albini, Angelo Photochemistry and Photobiology, 2006 , vol. 82, # 1 p. 225 - 230]

More Articles...